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pentobarbital will lessen the extent or impact of colchicine by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Observe.pentobarbital will lessen the level or result of bexarotene by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Observe.pentobarbital will minimize the extent or impact of ethotoin by impacting